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Digital Slide Scanning and Application System

Motic’s new Digital Slide Scanning solution combines a motorized microscope platform with slide scanning and control software enabling a traditional glass slide to be quickly scanned and assembled at various magnifications.

These digitally-scanned slides can be viewed on screen similar to the way a traditional slide can be viewed under a microscope. The user can select different fixed magnifications (2x, 4x, 10x, 20x, 40x, 100x) or can seamlessly zoom in and out of the image (1x to 100x). This allows closer inspection of any area of interest without losing image clarity and resolution.

Motic’s Virtual Microscopy solution can be extended to multiple viewers when it is connected to a local network. Digital Slides can easily be archived, managed, annotated and diagnosed by a third party without time and geographical limitations. This flexible system can be applied in fields as diverse as Education, Diagnostics in Pathology, Clinical-Lab Remote Consultation and Scientific Research.

Integration with other Motic solutions is also possible. This Digital Slide system can be integrated into Motic’s DigiLab II network platform to teach and lecture more efficiently; it can be used to establish a slide gallery for classroom reference and administration, quantitative analysis or comparison.

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Microscope-based Scanning System
Motic’s Slide Scanning System is not based on the Black-Box concept of a completely enclosed scanner with single magnifications. Being a microscope-based solution, with a live-viewing option at all times, any user is able to verify accuracy of colour, focal plane or illumination settings through the eyepieces providing total quality control. With high-resolution scans of delicate and important samples, users can feel reassured in knowing they can check and confirm that the digital result matches the true optical image.

Components

Auto-Scanning Platform
Motic’s auto-scanning microscope platform coordinates the four key automatic functions of the microscope: changing magnifications, scanning along x/y axis and focusing on the Z axis. A slide is usually scanned at higher magnifications (mostly 40x) to allow easy navigation and zooming without loss of details and guarantees repeatability when compared to simple viewing.

Motic has taken great care in ensuring accuracy, reliability and repeatability with this platform. The deviation of its micro-servos for finding repetitive locations is less than 1 micron for X, Y and Z. Coordination of all drives with the software is controlled by a modularized control box.

Motic Pro Series True Color CCD
The Moticam Pro Series camera is modular, and is easily making the whole system upgradeable as time passes. The standard for this platform is Motic’s MoticPro 285A camera with a 2/3” Sony CCD 12-bit sensor boasting 6.45μm x 6.45μm pixels.

Whatever Motic CCD camera is used, this system operates as an integrated platform swiftly converting traditional glass slides into high-resolution digital archives. A traditional glass slide can be digitized into a standard digital file sizes of approx. 1 Gig.

Repeatble and Efficient control for reliable results

At the core of Motic’s Virtual Slide Scanning System, an easy-to-use software interface offers all controls to quickly scan, process and digitize a slide.

  • A comprehensive setup and calibration program ensures that the system is able to repeatedly scan high-quality images by automatically calculating adjustments for minor illumination and optical differences. Alignments of the imaging sensor offset can be compensated to an accuracy of up to 0.1 degrees.
  • Automatic control and execution of scanning, focusing and multi-field observation under variable magnifications
  • Automatic compensation for uneven slides through multi-point auto-focusing algorithms
  • High resolution whole-slide scanning with different models such as standard quick scanning, high-precision scanning and multi-focus scanning
  • Encryption function for access control
  • Annotation and Editing for easy archiving and retrieval Side-by-Side Viewing for immediate image comparisons
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